Vitamin-dependent Gene Databases
This vitamin-dependent database lists all known gene products with domains using either vitamin B1 (thiamine), B2 (riboflavin), or B3 (niacin) as a co-factor or substrate (Penberthy, 2013).
One can search for their gene of interest within this webpage or download the spreadsheet at the end of this webpage.
This is a continuously important resource as science continues to determine gene-functions and by extension vitamin B1-B3 functions.
Genetic polymorphisms that reduce vitamin (derived) co-factor/substrate-binding affinity result in individuals whose lives can be saved, improved, or optimized by high-dose vitamin therapy (Ames, 2002). This is true for countless numbers of individuals. It costs almost nothing to do high-dose vitamin therapy and the safety profile is superior to most pharmaceuticals.
It may be clinically significant to consider genetic polymorphisms in the genes containing NAD, thiamine, and/or riboflavin-binding domains.
These databases were developed from my own research using UniproKB with the assistance of Dr. Kristian Axelsen of the Swiss Institute of Bioinformatics, 2012.
Databases are freely available for download at the bottom of this page.
Niacin is particularly impressive for many reasons not limited to the following. The biochemical end-product of niacin consumption, nicotinamide adenine dinucleotide (NAD), is used a co-factor or substrate in more reactions than any other vitamin-derived co-factor, >450 reactions. A polymorphism in the NAD binding for any of these genes can cause an individual to require higher amounts of niacin to provide greater NAD concentrations. NAD is used in phase 1 drug metabolism, including basic alcohol metabolism, where the founder of Alcoholics Anonymous himself, Bill W, was a great proponent of its use in controlling alcoholism (Niacin Therapy as Used by Abram Hoffer). We know more about several mechanisms that specifically and actively trigger the depletion of NAD than we do for most vitamins (Penberthy, 2007; Penberthy, 2009). Niacin-related research continues to amaze, with the PARP, Sirtuin, CD38, drug metabolism fields, and more all giving perennial consideration to this amazing molecule.
Thiamine, while only involved in roughly 30 different reactions, thiamine is essential for several central bioenergetic pathways that are particularly important in preventing neurodegeneration and powering the heart. Thiamine is distinguished as the heat-sensitive B vitamin. Absence of thiamine essentially causes the brain to rot and favorable results have been seen after high-dose administration for a variety of neurological conditions. Thiamine is routinely administered by injection to treat Wernicke-Korsakoff syndrome, which most frequently occurs in chronic alcoholics. Recovery from nystagmus can occur within minutes of injection. Most, unfortunately, thiamine research is woefully overlooked, but it makes sense as consideration for neurodegenerative diseases like Alzheimer's.
Riboflavin is the most colorful vitamin. While it is difficult to achieve high doses of this B vitamin due to poor solubility, something is everything when it is essential. It is used in a wide range of reactions (>200). Unfortunately, the mechanisms of riboflavin depletion are poorly understood and this vitamin is generally understudied.
Ames BN, Elson-Schwab I, Silver EA. High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms. Am J Clin Nutr. Apr 2002;75(4):616-658.
Penberthy WT. Niacin, Riboflavin, and Thiamine. In: Stipanuk MH, Caudill MA, eds. Biochemical, physiological, and molecular aspects of human nutrition. 3rd ed. St. Louis, Mo.: Elsevier/Saunders; 2013:p.540-564.
Penberthy WT. Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease. Curr Drug Metab. Apr 2007;8(3):245-266.
Penberthy WT, Tsunoda I. The importance of NAD in multiple sclerosis. Curr Pharm Des. 2009;15(1):64-99.
|
|
NAD(P(H))/VitB3 Dependent |
|
||
|
|
Gene |
|
Protein Name |
|
|
|
AASS |
|
Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] |
|
|
|
ACMSD |
|
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) (Picolinate carboxylase) |
|
|
|
ADH1A ADH1 |
|
Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha) |
|
|
|
ADH1B ADH2 |
|
Alcohol dehydrogenase 1B (EC 1.1.1.1) (Alcohol dehydrogenase subunit beta) |
|
|
|
ADH1C ADH3 |
|
Alcohol dehydrogenase 1C (EC 1.1.1.1) (Alcohol dehydrogenase subunit gamma) |
|
|
|
ADH4 |
|
Alcohol dehydrogenase 4 (EC 1.1.1.1) (Alcohol dehydrogenase class II pi chain) |
|
|
|
ADH5 ADHX FDH |
|
Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase class chi chain) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284) (Glutathione-dependent formaldehyde dehydrogenase) (GSH-FDH) (FALDH) (FDH) (EC 1.1.1.-) |
|
|
|
ADH6 |
|
Alcohol dehydrogenase 6 (EC 1.1.1.1) |
|
|
|
ADH7 |
|
Alcohol dehydrogenase class 4 mu/sigma chain (EC 1.1.1.1) (Alcohol dehydrogenase class IV mu/sigma chain) (Retinol dehydrogenase) (Gastric alcohol dehydrogenase) |
|
|
|
AFMID |
|
Probable arylformamidase (EC 3.5.1.9) (Kynurenine formamidase) (KF) |
|
|
|
AHCY SAHH |
|
Adenosylhomocysteinase (AdoHcyase) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) |
|
|
|
AHCYL1 DCAL XPVKONA |
|
Putative adenosylhomocysteinase 2 (AdoHcyase 2) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase 2) (S-adenosylhomocysteine hydrolase-like protein 1) (DC-expressed AHCY-like molecule) |
|
|
|
AHCYL2 KIAA0828 |
|
Putative adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2) |
|
|
|
AKR1A1 ALDR1 ALR |
|
Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1) |
|
|
|
AKR1B1 ALDR1 |
|
Aldose reductase (AR) (EC 1.1.1.21) (Aldehyde reductase) (Aldo-keto reductase family 1 member B1) |
|
|
|
AKR1C1 DDH DDH1 |
|
Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Indanol dehydrogenase) (EC 1.1.1.112) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2) (Chlordecone reductase homolog HAKRC) (High-affinity hepatic bile acid-binding protein) (HBAB) |
|
|
|
AKR1C2 DDH2 |
|
Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Chlordecone reductase homolog HAKRD) |
|
|
|
AKR1C3 DDH1 HSD17B5 KIAA0119 PGFS |
|
Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (3-alpha-HSD type 2) (EC 1.1.1.213) (3-alpha-HSD type II, brain) (Testosterone 17-beta-dehydrogenase 5) (EC 1.1.1.63) (EC 1.1.1.64) (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (Prostaglandin F synthase) (PGFS) (EC 1.1.1.188) (Indanol dehydrogenase) (EC 1.1.1.112) (Dihydrodiol dehydrogenase type I) (Dihydrodiol dehydrogenase 3) (DD-3) (DD3) (Chlordecone reductase homolog HAKRb) (HA1753) |
|
|
|
AKR1C4 CHDR |
|
Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (Chlordecone reductase) (CDR) (EC 1.1.1.225) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA) |
|
|
|
AKR1D1 SRD5B1 |
|
3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) |
|
|
|
AKR1E2 AKR1CL2 AKRDC1 |
|
1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (Testis-specific protein) (hTSP) (LoopADR) |
|
|
|
AKR7A2 AFAR AFAR1 AKR7 |
|
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) |
|
|
|
ALDH18A1 GSAS P5CS PYCS |
|
Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] |
|
|
|
ALDH1A1 ALDC ALDH1 PUMB1 |
|
Retinal dehydrogenase 1 (RALDH 1) (RalDH1) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) |
|
|
|
ALDH1A2 RALDH2 |
|
Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II)) |
|
|
|
ALDH1A3 ALDH6 |
|
Aldehyde dehydrogenase family 1 member A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) (RalDH3) |
|
|
|
ALDH1B1 ALDH5 ALDHX |
|
Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase family 1 member B1) (Aldehyde dehydrogenase 5) |
|
|
|
ALDH1L1 FTHFD |
|
10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) |
|
|
|
ALDH1L2 |
|
Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2 (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2) |
|
|
|
ALDH2 ALDM |
|
Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDHI) (ALDH-E2) |
|
|
|
ALDH3A1 ALDH3 |
|
Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (Aldehyde dehydrogenase family 3 member A1) (Aldehyde dehydrogenase 3) (ALDHIII) |
|
|
|
ALDH3A2 ALDH10 FALDH |
|
Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10) (Microsomal aldehyde dehydrogenase) |
|
|
|
ALDH3B1 ALDH7 |
|
Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7) |
|
|
|
ALDH3B2 ALDH8 |
|
Aldehyde dehydrogenase family 3 member B2 (EC 1.2.1.5) (Aldehyde dehydrogenase 8) |
|
|
|
ALDH4A1 ALDH4 P5CDH |
|
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.5.1.12) (Aldehyde dehydrogenase family 4 member A1) |
|
|
|
ALDH5A1 SSADH |
|
Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) (Aldehyde dehydrogenase family 5 member A1) |
|
|
|
ALDH6A1 MMSDH |
|
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Malonate-semialdehyde dehydrogenase [acylating]) (MMSDH) (EC 1.2.1.27) (EC 1.2.1.18) (Aldehyde dehydrogenase family 6 member A1) |
|
|
|
ALDH7A1 ATQ1 |
|
Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) |
|
|
|
ALDH8A1 ALDH12 |
|
Aldehyde dehydrogenase family 8 member A1 (EC 1.2.1.-) (Aldehyde dehydrogenase 12) |
|
|
|
ALDH9A1 ALDH4 ALDH7 ALDH9 |
|
4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Aldehyde dehydrogenase E3 isozyme) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) |
|
|
|
ART1 |
|
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 (EC 2.4.2.31) (Mono(ADP-ribosyl)transferase 1) (CD antigen CD296) |
|
|
|
ART3 TMART |
|
Ecto-ADP-ribosyltransferase 3 (EC 2.4.2.31) (NAD(P)(+)--arginine ADP-ribosyltransferase 3) (Mono(ADP-ribosyl)transferase 3) |
|
|
|
ART4 DO DOK1 |
|
Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (NAD(P)(+)--arginine ADP-ribosyltransferase 4) (Mono(ADP-ribosyl)transferase 4) (Dombrock blood group carrier molecule) (CD antigen CD297) |
|
|
|
ART5 UNQ575/PRO1137 |
|
Ecto-ADP-ribosyltransferase 5 (EC 2.4.2.31) (NAD(P)(+)--arginine ADP-ribosyltransferase 5) (Mono(ADP-ribosyl)transferase 5) |
|
|
|
ASPDH |
|
Putative L-aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain-containing protein) |
|
|
|
ASPDH |
|
Putative L-aspartate dehydrogenase (EC 1.4.1.21) (Aspartate dehydrogenase domain-containing protein) |
|
|
|
BDH1 BDH |
|
D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH) (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) |
|
|
|
BDH2 DHRS6 UNQ6308/PRO20933 |
|
3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.30) (R-beta-hydroxybutyrate dehydrogenase) (Dehydrogenase/reductase SDR family member 6) (Oxidoreductase UCPA) |
|
|
|
BLVRA BLVR BVR |
|
Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase) |
|
|
|
BLVRB FLR |
|
Flavin reductase (FR) (EC 1.5.1.30) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) |
|
|
|
BST1 |
|
ADP-ribosyl cyclase 2 (EC 3.2.2.5) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Bone marrow stromal antigen 1) (BST-1) (CD antigen CD157) |
|
|
|
C8orf38 |
|
UPF0551 protein C8orf38, mitochondrial (Putative phytoene synthase) |
|
|
|
CAT |
|
Catalase (EC 1.11.1.6) |
|
|
|
CBR1 CBR CRN |
|
Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 1) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) (Prostaglandin 9-ketoreductase) (15-hydroxyprostaglandin dehydrogenase [NADP+]) (EC 1.1.1.197) |
|
|
|
CBR3 |
|
Carbonyl reductase [NADPH] 3 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 3) |
|
|
|
CBR4 |
|
Carbonyl reductase family member 4 (EC 1.-.-.-) (Quinone reductase CBR4) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) |
|
|
|
CD38 |
|
ADP-ribosyl cyclase 1 (EC 3.2.2.5) (Cyclic ADP-ribose hydrolase 1) (cADPr hydrolase 1) (T10) (CD antigen CD38) |
|
|
|
CRYL1 CRY |
|
Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) |
|
|
|
CRYZ |
|
Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) |
|
|
|
CTBP1 CTBP |
|
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) |
|
|
|
CYB5B CYB5M OMB5 |
|
Cytochrome b5 type B (Cytochrome b5 outer mitochondrial membrane isoform) |
|
|
|
CYB5R1 NQO3A2 UNQ3049/PRO9865 |
|
NADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2) (Humb5R2) |
|
|
|
CYB5R2 |
|
NADH-cytochrome b5 reductase 2 (b5R.2) (EC 1.6.2.2) |
|
|
|
CYB5R3 DIA1 |
|
NADH-cytochrome b5 reductase 3 (Cytochrome b5 reductase) (B5R) (EC 1.6.2.2) (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form] |
|
|
|
CYB5R4 NCB5OR |
|
Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R) (N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein) |
|
|
|
CYB5RL |
|
NADH-cytochrome b5 reductase-like (EC 1.6.2.2) |
|
|
|
CYBA |
|
Cytochrome b-245 light chain (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 22 kDa polypeptide) (p22-phox) (p22phox) (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Superoxide-generating NADPH oxidase light chain subunit) |
|
|
|
CYBB NOX2 |
|
Cytochrome b-245 heavy chain (EC 1.-.-.-) (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 91 kDa polypeptide) (Heme-binding membrane glycoprotein gp91phox) (CGD91-phox) (gp91-phox) (gp91-1) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Superoxide-generating NADPH oxidase heavy chain subunit) (NADPH oxidase 2) |
|
|
|
CYP1A1 |
|
Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (Cytochrome P450-P1) (Cytochrome P450 form 6) (Cytochrome P450-C) |
|
|
|
CYP1A2 |
|
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cytochrome P450-P3) (Cytochrome P(3)450) (Cytochrome P450 4) |
|
|
|
CYP1B1 |
|
Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) |
|
|
|
CYP24A1 CYP24 |
|
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (Vitamin D(3) 24-hydroxylase) (24-OHase) (EC 1.14.13.n4) (Cytochrome P450 24A1) (Cytochrome P450-CC24) |
|
|
|
CYP27A1 CYP27 |
|
Sterol 26-hydroxylase, mitochondrial (EC 1.14.13.15) (Cytochrome P450 27) (Cytochrome P-450C27/25) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) |
|
|
|
CYP27B1 CYP1ALPHA CYP27B |
|
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1-alpha-hydroxylase) (VD3 1A hydroxylase) (Cytochrome P450C1 alpha) (Cytochrome P450VD1-alpha) |
|
|
|
CYP2A7 |
|
Cytochrome P450 2A7 (EC 1.14.14.1) (CYPIIA7) (Cytochrome P450 IIA4) |
|
|
|
CYP2B6 |
|
Cytochrome P450 2B6 (EC 1.14.14.1) (CYPIIB6) (Cytochrome P450 IIB1) |
|
|
|
CYP2C19 |
|
Cytochrome P450 2C19 ((R)-limonene 6-monooxygenase) (EC 1.14.13.80) ((S)-limonene 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 7-monooxygenase) (EC 1.14.13.49) (CYPIIC19) (Cytochrome P450-11A) (Mephenytoin 4-hydroxylase) (CYPIIC17) (Cytochrome P450-254C) |
|
|
|
CYP2C8 |
|
Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (Cytochrome P450 form 1) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 IIC2) (S-mephenytoin 4-hydroxylase) |
|
|
|
CYP2C9 CYP2C10 |
|
Cytochrome P450 2C9 ((R)-limonene 6-monooxygenase) (EC 1.14.13.80) ((S)-limonene 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 7-monooxygenase) (EC 1.14.13.49) (CYPIIC9) (Cytochrome P450 PB-1) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (S-mephenytoin 4-hydroxylase) (Cytochrome P-450MP) |
|
|
|
CYP2E1 CYP2E |
|
Cytochrome P450 2E1 (EC 1.14.13.-) (CYPIIE1) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (Cytochrome P450-J) |
|
|
|
CYP2J2 |
|
Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic acid epoxygenase) |
|
|
|
CYP2R1 |
|
Vitamin D 25-hydroxylase (EC 1.14.13.15) (Cytochrome P450 2R1) |
|
|
|
CYP39A1 |
|
24-hydroxycholesterol 7-alpha-hydroxylase (Oxysterol 7-alpha-hydroxylase) (EC 1.14.13.99) (Cytochrome P450 39A1) (hCYP39A1) |
|
|
|
CYP3A4 CYP3A3 |
|
Cytochrome P450 3A4 (Quinine 3-monooxygenase) (EC 1.14.13.67) (CYPIIIA4) (Nifedipine oxidase) (Cytochrome P450 3A3) (CYPIIIA3) (Cytochrome P450 HLp) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Albendazole monooxygenase) (EC 1.14.13.32) (Albendazole sulfoxidase) |
|
|
|
CYP3A5 |
|
Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3) (Cytochrome P450 HLp2) |
|
|
|
CYP3A7 |
|
Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA) |
|
|
|
CYP46A1 CYP46 |
|
Cholesterol 24-hydroxylase (CH24H) (EC 1.14.13.98) (Cytochrome P450 46A1) |
|
|
|
CYP4B1 |
|
Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450-HP) |
|
|
|
CYP4F2 |
|
Leukotriene-B(4) omega-hydroxylase 1 (EC 1.14.13.30) (Cytochrome P450 4F2) (CYPIVF2) (Leukotriene-B(4) 20-monooxygenase 1) (Cytochrome P450-LTB-omega) |
|
|
|
CYP4F3 LTB4H |
|
Leukotriene-B(4) omega-hydroxylase 2 (EC 1.14.13.30) (Cytochrome P450 4F3) (CYPIVF3) (Leukotriene-B(4) 20-monooxygenase 2) (Cytochrome P450-LTB-omega) |
|
|
|
CYP51A1 CYP51 |
|
Lanosterol 14-alpha demethylase (LDM) (EC 1.14.13.70) (Cytochrome P450 51A1) (CYPLI) (Cytochrome P450LI) (Sterol 14-alpha demethylase) (Cytochrome P450-14DM) (Cytochrome P45014DM) |
|
|
|
CYP7A1 CYP7 |
|
Cholesterol 7-alpha-monooxygenase (EC 1.14.13.17) (Cytochrome P450 7A1) (CYPVII) (Cholesterol 7-alpha-hydroxylase) |
|
|
|
CYP7B1 |
|
25-hydroxycholesterol 7-alpha-hydroxylase (Oxysterol 7-alpha-hydroxylase) (EC 1.14.13.100) (Cytochrome P450 7B1) |
|
|
|
CYP8B1 CYP12 |
|
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.13.95) (Cytochrome P450 8B1) (CYPVIIIB1) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (Sterol 12-alpha-hydroxylase) |
|
|
|
DCXR |
|
L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase) (Kidney dicarbonyl reductase) (kiDCR) (Carbonyl reductase II) (Sperm surface protein P34H) |
|
|
|
DECR1 DECR |
|
2,4-dienoyl-CoA reductase, mitochondrial (EC 1.3.1.34) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) |
|
|
|
DECR2 PDCR |
|
Peroxisomal 2,4-dienoyl-CoA reductase (pDCR) (EC 1.3.1.34) (2,4-dienoyl-CoA reductase 2) |
|
|
|
DHCR7 D7SR |
|
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Sterol Delta(7)-reductase) (Putative sterol reductase SR-2) |
|
|
|
DHDH 2DD |
|
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (Dimeric dihydrodiol dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (D-xylose 1-dehydrogenase) (Hum2DD) |
|
|
|
DHFR; DHFRP1 |
|
Dihydrofolate reductase (EC 1.5.1.3) |
|
|
|
DHPS DS |
|
Deoxyhypusine synthase (DHS) (EC 2.5.1.46) |
|
|
|
DHRS2 |
|
Dehydrogenase/reductase SDR family member 2 (EC 1.1.1.-) (Protein D) (Dicarbonyl reductase HEP27) |
|
|
|
DHRS3 UNQ2424/PRO4983 |
|
Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (DD83.1) |
|
|
|
DHRS4 UNQ851/PRO1800 |
|
Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (Short-chain dehydrogenase/reductase family member 4) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (PHCR) (CR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (SCAD-SRL) |
|
|
|
DHRS9 UNQ835/PRO1773 |
|
Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (Short-chain dehydrogenase/reductase retSDR8) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) |
|
|
|
DLD GCSL LAD PHE3 |
|
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) |
|
|
|
DPYD |
|
Dihydropyrimidine dehydrogenase [NADP+] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase) |
|
|
|
DUOX1 DUOX LNOX1 THOX1 |
|
Dual oxidase 1 (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Large NOX 1) (Long NOX 1) (Thyroid oxidase 1) |
|
|
|
DUOX2 LNOX2 THOX2 |
|
Dual oxidase 2 (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Large NOX 2) (Long NOX 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) |
|
|
|
ECSIT |
|
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC) |
|
|
|
EHHADH ECHD |
|
Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)] |
|
|
|
ENOX1 PIG38 |
|
Ecto-NOX disulfide-thiol exchanger 1 (Constitutive Ecto-NOX) (cNOX) (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] |
|
|
|
ENOX2 COVA1 |
|
Ecto-NOX disulfide-thiol exchanger 2 (Tumor-associated hydroquinone oxidase) (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] |
|
|
|
ENPP3 PDNP3 |
|
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9)] |
|
|
|
FAR1 MLSTD2 UNQ2423/PRO4981 |
|
Fatty acyl-CoA reductase 1 (EC 1.2.1.n2) (Male sterility domain-containing protein 2) |
|
|
|
FAR2 MLSTD1 |
|
Fatty acyl-CoA reductase 2 (EC 1.2.1.n2) (Male sterility domain-containing protein 1) |
|
|
|
FASN FAS |
|
Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] |
|
|
|
FDFT1 |
|
Squalene synthase (SQS) (SS) (EC 2.5.1.21) (Farnesyl-diphosphate farnesyltransferase) (FPP:FPP farnesyltransferase) |
|
|
|
FDXR ADXR |
|
NADPH:adrenodoxin oxidoreductase, mitochondrial (Adrenodoxin reductase) (AR) (EC 1.18.1.2) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase) |
|
|
|
FMO1 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1) |
|
|
|
FMO2 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (FMO 1B1) (Dimethylaniline oxidase 2) |
|
|
|
FMO3 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (FMO form 2) (FMO II) (Dimethylaniline oxidase 3) |
|
|
|
FMO4 FMO2 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4) |
|
|
|
FMO5 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5) |
|
|
|
FMO6P FMO6 |
|
Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6) |
|
|
|
FOXO4 AFX AFX1 MLLT7 |
|
Forkhead box protein O4 (Fork head domain transcription factor AFX1) |
|
|
|
G6PD |
|
Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49) |
|
|
|
GALE |
|
UDP-glucose 4-epimerase (EC 5.1.3.2) (UDP-galactose 4-epimerase) (Galactowaldenase) |
|
|
|
GAPDH GAPD CDABP0047 OK/SW-cl.12 |
|
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) |
|
|
|
GAPDHS GAPD2 GAPDH2 GAPDS HSD35 HSD-35 |
|
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic glyceraldehyde-3-phosphate dehydrogenase) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2) |
|
|
|
GLRX GRX |
|
Glutaredoxin-1 (Thioltransferase-1) (TTase-1) |
|
|
|
GLUD1 GLUD |
|
Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3) |
|
|
|
GLUD2 GLUDP1 |
|
Glutamate dehydrogenase 2, mitochondrial (GDH 2) (EC 1.4.1.3) |
|
|
|
GLYR1 HIBDL NP60 |
|
Putative oxidoreductase GLYR1 (EC 1.-.-.-) (Glyoxylate reductase 1 homolog) (3-hydroxyisobutyrate dehydrogenase-like protein) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Cytokine-like nuclear factor N-PAC) |
|
|
|
GMDS |
|
GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD) |
|
|
|
GMPR GMPR1 |
|
GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1) |
|
|
|
GMPR2 |
|
GMP reductase 2 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2) |
|
|
|
GPD1 |
|
Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic (GPDH-C) (GPD-C) (EC 1.1.1.8) |
|
|
|
GPD1L KIAA0089 |
|
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1-L) (EC 1.1.1.8) |
|
|
|
GRHPR GLXR MSTP035 |
|
Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81) |
|
|
|
GSR GLUR GRD1 |
|
Glutathione reductase, mitochondrial (GRase) (GR) (EC 1.8.1.7) |
|
|
|
H6PD GDH |
|
GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase (EC 1.1.1.47) (Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] |
|
|
|
HAAO |
|
3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilic acid dioxygenase) (HAD) (3-hydroxyanthranilate oxygenase) (3-HAO) |
|
|
|
HADH HAD HADHSC SCHAD |
|
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Short-chain 3-hydroxyacyl-CoA dehydrogenase) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) |
|
|
|
HADHA HADH |
|
Trifunctional enzyme subunit alpha, mitochondrial (TP-alpha) (78 kDa gastrin-binding protein) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] |
|
|
|
HIBADH |
|
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) |
|
|
|
HMGCR |
|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34) |
|
|
|
HPGD PGDH1 |
|
15-hydroxyprostaglandin dehydrogenase [NAD+] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1) |
|
|
|
HSD11B1 HSD11 HSD11L |
|
Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11-DH) |
|
|
|
HSD11B2 HSD11K |
|
Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (11-DH2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) |
|
|
|
HSD17B1 E17KSR EDH17B1 EDH17B2 EDHB17 |
|
Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 1) (17-beta-HSD 1) (Placental 17-beta-hydroxysteroid dehydrogenase) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) |
|
|
|
HSD17B10 ERAB HADH2 MRPP2 SCHAD XH98G2 |
|
3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Short-chain type dehydrogenase/reductase XH98G2) |
|
|
|
HSD17B11 DHRS8 PAN1B PSEC0029 UNQ207/PRO233 |
|
Estradiol 17-beta-dehydrogenase 11 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17betaHSD11) (17bHSD11) (17-beta-hydroxysteroid dehydrogenase XI) (17-beta-HSD XI) (17betaHSDXI) (Dehydrogenase/reductase SDR family member 8) (Retinal short-chain dehydrogenase/reductase 2) (retSDR2) (Cutaneous T-cell lymphoma-associated antigen HD-CL-03) (CTCL-associated antigen HD-CL-03) |
|
|
|
HSD17B12 |
|
Estradiol 17-beta-dehydrogenase 12 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (EC 1.3.1.-) |
|
|
|
HSD17B14 DHRS10 SDR3 UNQ502/PRO474 |
|
17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (Dehydrogenase/reductase SDR family member 10) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Retinal short-chain dehydrogenase/reductase retSDR3) |
|
|
|
HSD17B2 EDH17B2 |
|
Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.63) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) |
|
|
|
HSD17B4 EDH17B4 |
|
Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase (EC 4.2.1.107)] |
|
|
|
HSD17B6 RODH |
|
17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6) (17-beta-HSD6) (EC 1.1.1.62) (EC 1.1.1.63) (EC 1.1.1.105) (Oxidative 3-alpha hydroxysteroid dehydrogenase) (3-alpha->beta-hydroxysteroid epimerase) (3-alpha->beta-HSE) |
|
|
|
HSD17B7 UNQ2563/PRO6243 |
|
3-keto-steroid reductase (EC 1.1.1.270) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) |
|
|
|
HSD17B8 FABGL HKE6 RING2 |
|
Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.63) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Protein Ke6) (Ke-6) (Really interesting new gene 2 protein) |
|
|
|
HSD3B1 3BH HSDB3A |
|
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I) (3-beta-HSD I) (Trophoblast antigen FDO161G) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)] |
|
|
|
HSD3B2 HSDB3B |
|
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II) (3-beta-HSD II) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)] |
|
|
|
HSD3B7 |
|
3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3-beta-HSD VII) (3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase) (C(27) 3-beta-HSD) (EC 1.1.1.-) (Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase) (EC 1.1.1.181) |
|
|
|
HTATIP2 CC3 TIP30 |
|
Oxidoreductase HTATIP2 (EC 1.1.1.-) (HIV-1 TAT-interactive protein 2) (30 kDa HIV-1 TAT-interacting protein) |
|
|
|
IDH1 PICD |
|
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (Oxalosuccinate decarboxylase) (NADP(+)-specific ICDH) (IDP) |
|
|
|
IDH2 |
|
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (NADP(+)-specific ICDH) (IDP) (ICD-M) |
|
|
|
IDH3A |
|
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha) |
|
|
|
IDH3B |
|
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta) |
|
|
|
IDH3G |
|
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit gamma) (NAD(+)-specific ICDH subunit gamma) |
|
|
|
IMPDH1 IMPD1 |
|
Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPDH 1) (IMPD 1) (EC 1.1.1.205) (IMPDH-I) |
|
|
|
IMPDH2 IMPD2 |
|
Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPDH 2) (IMPD 2) (EC 1.1.1.205) (IMPDH-II) |
|
|
|
ISYNA1 INO1 |
|
Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol-1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1) |
|
|
|
ITGB1BP3 NRK2 |
|
Nicotinamide riboside kinase 2 (NmR-K 2) (NRK 2) (EC 2.7.1.22) (Ribosylnicotinamide kinase 2) (RNK 2) (Nicotinic acid riboside kinase 2) (EC 2.7.1.n4) (Ribosylnicotinic acid kinase 2) (Integrin beta-1-binding protein 3) (Muscle integrin-binding protein) (MIBP) |
|
|
|
IYD C6orf71 DEHAL1 |
|
Iodotyrosine dehalogenase 1 (IYD-1) (EC 1.-.-.-) |
|
|
|
KDSR FVT1 |
|
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) |
|
|
|
KMO |
|
Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase) |
|
|
|
KYNU |
|
Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) |
|
|
|
LDHA PIG19 |
|
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59) (Cell proliferation-inducing gene 19 protein) |
|
|
|
LDHAL6A LDHL2 |
|
L-lactate dehydrogenase A-like 6A (EC 1.1.1.27) |
|
|
|
LDHAL6B LDHAL6 LDHL |
|
L-lactate dehydrogenase A-like 6B (EC 1.1.1.27) |
|
|
|
LDHB |
|
L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46) |
|
|
|
LDHC |
|
L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (LDH testis subunit) (LDH-X) (Cancer/testis antigen 32) (CT32) |
|
|
|
MDH2 |
|
Malate dehydrogenase, mitochondrial (EC 1.1.1.37) |
|
|
|
ME1 |
|
NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) |
|
|
|
ME2 |
|
NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2) |
|
|
|
ME3 |
|
NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3) |
|
|
|
MECR NBRF1 CGI-63 |
|
Trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38) (Nuclear receptor-binding factor 1) (NRBF-1) (HsNrbf-1) |
|
|
|
MOSC2 |
|
MOSC domain-containing protein 2, mitochondrial (EC 1.-.-.-) |
|
|
|
MT-ND1 MTND1 NADH1 ND1 |
|
NADH-ubiquinone oxidoreductase chain 1 (EC 1.6.5.3) (NADH dehydrogenase subunit 1) |
|
|
|
MT-ND2 MTND2 NADH2 ND2 |
|
NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3) (NADH dehydrogenase subunit 2) |
|
|
|
MT-ND3 MTND3 NADH3 ND3 |
|
NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3) (NADH dehydrogenase subunit 3) |
|
|
|
MT-ND4 MTND4 NADH4 ND4 |
|
NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3) (NADH dehydrogenase subunit 4) |
|
|
|
MT-ND4L MTND4L NADH4L ND4L |
|
NADH-ubiquinone oxidoreductase chain 4L (EC 1.6.5.3) (NADH dehydrogenase subunit 4L) |
|
|
|
MT-ND5 MTND5 NADH5 ND5 |
|
NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3) (NADH dehydrogenase subunit 5) |
|
|
|
MT-ND6 MTND6 NADH6 ND6 |
|
NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3) (NADH dehydrogenase subunit 6) |
|
|
|
MTHFD1 MTHFC MTHFD |
|
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)] |
|
|
|
MTHFD2 NMDMC |
|
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] |
|
|
|
MTHFD2L |
|
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] |
|
|
|
MTHFR |
|
Methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
|
|
MTRR |
|
Methionine synthase reductase (MSR) (EC 1.16.1.8) |
|
|
|
NADK |
|
NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) |
|
|
|
NADSYN1 |
|
Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) |
|
|
|
NAMPT PBEF PBEF1 |
|
Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin) |
|
|
|
NAPRT1 FHIP |
|
Nicotinate phosphoribosyltransferase (NAPRTase) (EC 2.4.2.11) (Nicotinate phosphoribosyltransferase domain-containing protein 1) (FHA-HIT-interacting protein) |
|
|
|
NCF1 NOXO2 SH3PXD1A |
|
Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (Nox-organizing protein 2) (Nox organizer 2) (SH3 and PX domain-containing protein 1A) |
|
|
|
NCF1B SH3PXD1B |
|
Putative neutrophil cytosol factor 1B (NCF-1B) (Putative SH3 and PX domain-containing protein 1B) |
|
|
|
NCF1C SH3PXD1C |
|
Putative neutrophil cytosol factor 1C (NCF-1C) (Putative SH3 and PX domain-containing protein 1C) |
|
|
|
NCF2 NOXA2 P67PHOX |
|
Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (NADPH oxidase activator 2) (67 kDa neutrophil oxidase factor) (p67-phox) |
|
|
|
NCF4 SH3PXD4 |
|
Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox) (SH3 and PX domain-containing protein 4) |
|
|
|
NDOR1 NR1 |
|
NADPH-dependent diflavin oxidoreductase 1 (EC 1.6.-.-) (Novel reductase 1) (NADPH-dependent FMN and FAD-containing oxidoreductase) |
|
|
|
NDUFA1 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (NADH-ubiquinone oxidoreductase MWFE subunit) (Complex I-MWFE) (CI-MWFE) |
|
|
|
NDUFA10 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (NADH-ubiquinone oxidoreductase 42 kDa subunit) (Complex I-42kD) (CI-42kD) |
|
|
|
NDUFA11 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (NADH-ubiquinone oxidoreductase subunit B14.7) (Complex I-B14.7) (CI-B14.7) |
|
|
|
NDUFA12 DAP13 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (NADH-ubiquinone oxidoreductase subunit B17.2) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (13 kDa differentiation-associated protein) |
|
|
|
NDUFA13 GRIM19 CGI-39 CDA016 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NADH-ubiquinone oxidoreductase B16.6 subunit) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic and interferon-induced mortality 19 protein) (Gene associated with retinoic and IFN-induced mortality 19 protein) (GRIM-19) (Cell death regulatory protein GRIM-19) |
|
|
|
NDUFA2 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (NADH-ubiquinone oxidoreductase B8 subunit) (Complex I-B8) (CI-B8) |
|
|
|
NDUFA3 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (NADH-ubiquinone oxidoreductase B9 subunit) (Complex I-B9) (CI-B9) |
|
|
|
NDUFA4 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 (NADH-ubiquinone oxidoreductase MLRQ subunit) (Complex I-MLRQ) (CI-MLRQ) |
|
|
|
NDUFA5 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (NADH-ubiquinone oxidoreductase 13 kDa-B subunit) (Complex I-13kD-B) (CI-13kD-B) (Complex I subunit B13) |
|
|
|
NDUFA6 LYRM6 NADHB14 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (NADH-ubiquinone oxidoreductase B14 subunit) (Complex I-B14) (CI-B14) (LYR motif-containing protein 6) |
|
|
|
NDUFA7 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (NADH-ubiquinone oxidoreductase subunit B14.5a) (Complex I-B14.5a) (CI-B14.5a) |
|
|
|
NDUFA8 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (NADH-ubiquinone oxidoreductase 19 kDa subunit) (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) |
|
|
|
NDUFA9 NDUFS2L |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Complex I-39kD) (CI-39kD) |
|
|
|
NDUFAB1 |
|
Acyl carrier protein, mitochondrial (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) (CI-SDAP) |
|
|
|
NDUFAF1 CIA30 CGI-65 |
|
Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1) |
|
|
|
NDUFAF3 C3orf60 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 |
|
|
|
NDUFAF4 C6orf66 HRPAP20 HSPC125 My013 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa) |
|
|
|
NDUFB1 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (NADH-ubiquinone oxidoreductase MNLL subunit) (Complex I-MNLL) (CI-MNLL) |
|
|
|
NDUFB10 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (NADH-ubiquinone oxidoreductase PDSW subunit) (Complex I-PDSW) (CI-PDSW) |
|
|
|
NDUFB11 UNQ111/PRO1064 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (NADH-ubiquinone oxidoreductase ESSS subunit) (Complex I-ESSS) (CI-ESSS) (Neuronal protein 17.3) (Np17.3) (p17.3) |
|
|
|
NDUFB2 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (NADH-ubiquinone oxidoreductase AGGG subunit) (Complex I-AGGG) (CI-AGGG) |
|
|
|
NDUFB3 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (NADH-ubiquinone oxidoreductase B12 subunit) (Complex I-B12) (CI-B12) |
|
|
|
NDUFB4 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (NADH-ubiquinone oxidoreductase B15 subunit) (Complex I-B15) (CI-B15) |
|
|
|
NDUFB5 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (NADH-ubiquinone oxidoreductase SGDH subunit) (Complex I-SGDH) (CI-SGDH) |
|
|
|
NDUFB6 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (NADH-ubiquinone oxidoreductase B17 subunit) (Complex I-B17) (CI-B17) |
|
|
|
NDUFB7 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (NADH-ubiquinone oxidoreductase B18 subunit) (Complex I-B18) (CI-B18) (Cell adhesion protein SQM1) |
|
|
|
NDUFB8 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (NADH-ubiquinone oxidoreductase ASHI subunit) (Complex I-ASHI) (CI-ASHI) |
|
|
|
NDUFB9 LYRM3 UQOR22 |
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NADH-ubiquinone oxidoreductase B22 subunit) (Complex I-B22) (CI-B22) (LYR motif-containing protein 3) |
|
|
|
NDUFC1 |
|
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (NADH-ubiquinone oxidoreductase KFYI subunit) (Complex I-KFYI) (CI-KFYI) |
|
|
|
NDUFC2 HLC1 |
|
NADH dehydrogenase [ubiquinone] 1 subunit C2 (NADH-ubiquinone oxidoreductase subunit B14.5b) (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) |
|
|
|
NDUFS1 |
|
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD) |
|
|
|
NDUFS2 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 49 kDa subunit) (Complex I-49kD) (CI-49kD) |
|
|
|
NDUFS3 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 30 kDa subunit) (Complex I-30kD) (CI-30kD) |
|
|
|
NDUFS4 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (NADH-ubiquinone oxidoreductase 18 kDa subunit) (Complex I-18 kDa) (CI-18 kDa) (Complex I-AQDQ) (CI-AQDQ) |
|
|
|
NDUFS5 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (NADH-ubiquinone oxidoreductase 15 kDa subunit) (Complex I-15 kDa) (CI-15 kDa) |
|
|
|
NDUFS6 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (NADH-ubiquinone oxidoreductase 13 kDa-A subunit) (Complex I-13kD-A) (CI-13kD-A) |
|
|
|
NDUFS7 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (Complex I-20kD) (CI-20kD) (PSST subunit) |
|
|
|
NDUFS8 |
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 23 kDa subunit) (Complex I-23kD) (CI-23kD) (TYKY subunit) |
|
|
|
NDUFV1 UQOR1 |
|
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 51 kDa subunit) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) |
|
|
|
NDUFV2 |
|
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 24 kDa subunit) |
|
|
|
NDUFV3 |
|
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (NADH-ubiquinone oxidoreductase 9 kDa subunit) (Complex I-9kD) (CI-9kD) (Renal carcinoma antigen NY-REN-4) |
|
|
|
NMNAT1 NMNAT |
|
Nicotinamide mononucleotide adenylyltransferase 1 (NMN adenylyltransferase 1) (EC 2.7.7.1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) (EC 2.7.7.18) |
|
|
|
NMNAT2 C1orf15 KIAA0479 |
|
Nicotinamide mononucleotide adenylyltransferase 2 (NMN adenylyltransferase 2) (EC 2.7.7.1) (Nicotinate-nucleotide adenylyltransferase 2) (NaMN adenylyltransferase 2) (EC 2.7.7.18) |
|
|
|
NMNAT3 FKSG76 |
|
Nicotinamide mononucleotide adenylyltransferase 3 (NMN adenylyltransferase 3) (Pyridine nucleotide adenylyltransferase 3) (PNAT-3) (EC 2.7.7.1) (Nicotinate-nucleotide adenylyltransferase 3) (NaMN adenylyltransferase 3) (EC 2.7.7.18) |
|
|
|
NMRAL1 HSCARG |
|
NmrA-like family domain-containing protein 1 |
|
|
|
NNT |
|
NAD(P) transhydrogenase, mitochondrial (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) |
|
|
|
NOS1 |
|
Nitric oxide synthase, brain (EC 1.14.13.39) (bNOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) |
|
|
|
NOS2 NOS2A |
|
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Hepatocyte NOS) (HEP-NOS) |
|
|
|
NOS3 |
|
Nitric oxide synthase, endothelial (EC 1.14.13.39) (Endothelial NOS) (eNOS) (EC-NOS) (NOS type III) (NOSIII) (Constitutive NOS) (cNOS) |
|
|
|
NOX1 MOX1 NOH1 |
|
NADPH oxidase 1 (NOX-1) (EC 1.-.-.-) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic oxidase 1) (MOX-1) |
|
|
|
NOX3 MOX2 |
|
NADPH oxidase 3 (EC 1.6.3.-) (gp91phox homolog 3) (GP91-3) (Mitogenic oxidase 2) (MOX-2) |
|
|
|
NOX4 RENOX |
|
NADPH oxidase 4 (EC 1.6.3.-) (Kidney superoxide-producing NADPH oxidase) (Kidney oxidase-1) (KOX-1) (Renal NAD(P)H-oxidase) |
|
|
|
NOX5 |
|
NADPH oxidase 5 (EC 1.6.3.-) |
|
|
|
NOXA1 P51NOX |
|
NADPH oxidase activator 1 (NOX activator 1) (P67phox-like factor) (p51-nox) (NCF2-like protein) (Antigen NY-CO-31) |
|
|
|
NQO1 DIA4 NMOR1 |
|
NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (QR1) (NAD(P)H:quinone oxidoreductase 1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase) |
|
|
|
NQO2 NMOR2 |
|
Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.99.2) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2) |
|
|
|
NRK1 C9orf95 |
|
Nicotinamide riboside kinase 1 (NmR-K 1) (NRK 1) (EC 2.7.1.22) (Ribosylnicotinamide kinase 1) (RNK 1) (Nicotinic acid riboside kinase 1) (EC 2.7.1.n4) (Ribosylnicotinic acid kinase 1) |
|
|
|
NSDHL H105E3 |
|
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3) |
|
|
|
NUDT12 |
|
Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12) |
|
|
|
NUDT7 |
|
Peroxisomal coenzyme A diphosphatase NUDT7 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 7) (Nudix motif 7) |
|
|
|
NXN NRX |
|
Nucleoredoxin (EC 1.8.1.8) |
|
|
|
P2Y1 P2RY1 |
|
Purinergic receptor p2y, g protein-coupled, 1; p2ry1 |
|
|
|
PARP1 ADPRT PPOL |
|
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) |
|
|
|
PARP10 |
|
Poly [ADP-ribose] polymerase 10 (PARP-10) (EC 2.4.2.30) |
|
|
|
PARP11 C12orf6 |
|
Poly [ADP-ribose] polymerase 11 (PARP-11) (EC 2.4.2.30) |
|
|
|
PARP12 ZC3HDC1 |
|
Poly [ADP-ribose] polymerase 12 (PARP-12) (EC 2.4.2.30) (Zinc finger CCCH domain-containing protein 1) |
|
|
|
PARP14 BAL2 KIAA1268 |
|
Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (B aggressive lymphoma protein 2) |
|
|
|
PARP15 BAL3 |
|
Poly [ADP-ribose] polymerase 15 (PARP-15) (EC 2.4.2.30) (B-aggressive lymphoma protein 3) |
|
|
|
PARP16 C15orf30 |
|
Poly [ADP-ribose] polymerase 16 (PARP-16) (EC 2.4.2.30) |
|
|
|
PARP2 ADPRT2 ADPRTL2 |
|
Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) |
|
|
|
PARP3 ADPRT3 ADPRTL3 |
|
Poly [ADP-ribose] polymerase 3 (PARP-3) (hPARP-3) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3) (IRT1) |
|
|
|
PARP4 ADPRTL1 KIAA0177 PARPL |
|
Poly [ADP-ribose] polymerase 4 (PARP-4) (EC 2.4.2.30) (Vault poly(ADP-ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) |
|
|
|
PARP6 |
|
Poly [ADP-ribose] polymerase 6 (PARP-6) (EC 2.4.2.30) |
|
|
|
PARP8 |
|
Poly [ADP-ribose] polymerase 8 (PARP-8) (EC 2.4.2.30) |
|
|
|
PARP9 BAL |
|
Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (B aggressive lymphoma protein) |
|
|
|
PECR PRO1004 |
|
Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (HPDHase) (pVI-ARL) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP) |
|
|
|
PGD PGDH |
|
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
|
|
|
PHGDH PGDH3 |
|
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) |
|
|
|
POR CYPOR |
|
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) |
|
|
|
PTGR1 LTB4DH |
|
Prostaglandin reductase 1 (PRG-1) (EC 1.3.1.-) (NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (EC 1.3.1.74) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) |
|
|
|
PTGR2 ZADH1 |
|
Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1) |
|
|
|
PYCR1 |
|
Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2) |
|
|
|
PYCR2 |
|
Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2) |
|
|
|
PYCRL |
|
Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein) |
|
|
|
QDPR DHPR |
|
Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase) |
|
|
|
QPRT |
|
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase) |
|
|
|
RAC2 |
|
Ras-related C3 botulinum toxin substrate 2 (p21-Rac2) (Small G protein) (GX) |
|
|
|
RDH10 UNQ9375/PRO34191 |
|
Retinol dehydrogenase 10 (EC 1.1.1.300) |
|
|
|
RDH11 ARSDR1 PSDR1 CGI-82 |
|
Retinol dehydrogenase 11 (EC 1.1.1.-) (Retinal reductase 1) (RalR1) (Prostate short-chain dehydrogenase/reductase 1) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) |
|
|
|
RDH12 |
|
Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis retinol dehydrogenase) |
|
|
|
RDH14 PAN2 UNQ529/PRO1072 |
|
Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2) |
|
|
|
RDH16 RODH4 |
|
Retinol dehydrogenase 16 (EC 1.1.-.-) (Sterol/retinol dehydrogenase) (Microsomal NAD+-dependent retinol dehydrogenase 4) (RoDH-4) |
|
|
|
RDH5 RDH1 |
|
11-cis retinol dehydrogenase (11-cis RDH) (EC 1.1.1.105) |
|
|
|
RDH8 PRRDH |
|
Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) |
|
|
|
RETSAT UNQ439/PRO872 |
|
All-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat) |
|
|
|
RRP8 KIAA0409 NML hucep-1 |
|
Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Nucleomethylin) (Cerebral protein 1) |
|
|
|
SC4MOL DESP4 ERG25 |
|
C-4 methylsterol oxidase (EC 1.14.13.72) (Methylsterol monooxygenase) |
|
|
|
SC5DL |
|
Lathosterol oxidase (EC 1.14.21.6) (Lathosterol 5-desaturase) (Delta(7)-sterol 5-desaturase) (C-5 sterol desaturase) (Sterol-C5-desaturase) |
|
|
|
SCCPDH CGI-49 |
|
Probable saccharopine dehydrogenase (EC 1.5.1.9) |
|
|
|
SDR16C5 RDHE2 |
|
Epidermal retinol dehydrogenase 2 (RDH-E2) (EPHD-2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) |
|
|
|
SDR9C7 RDHS SDRO |
|
Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S) |
|
|
|
SIRT1 SIR2L1 |
|
NAD-dependent deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (SIR2-like protein 1) (hSIR2) |
|
|
|
SIRT2 SIR2L SIR2L2 |
|
NAD-dependent deacetylase sirtuin-2 (EC 3.5.1.-) (SIR2-like protein 2) |
|
|
|
SIRT3 SIR2L3 |
|
NAD-dependent deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 3.5.1.-) (SIR2-like protein 3) |
|
|
|
SIRT4 SIR2L4 |
|
NAD-dependent ADP-ribosyltransferase sirtuin-4 (EC 2.4.2.-) (SIR2-like protein 4) |
|
|
|
SIRT5 SIR2L5 |
|
NAD-dependent deacetylase sirtuin-5 (EC 3.5.1.-) (SIR2-like protein 5) |
|
|
|
SIRT6 SIR2L6 |
|
NAD-dependent deacetylase sirtuin-6 (EC 3.5.1.-) (SIR2-like protein 6) |
|
|
|
SIRT7 SIR2L7 |
|
NAD-dependent deacetylase sirtuin-7 (EC 3.5.1.-) (SIR2-like protein 7) |
|
|
|
SLC25A1 SLC20A3 |
|
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) |
|
|
|
SORD |
|
Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase) |
|
|
|
SPR |
|
Sepiapterin reductase (SPR) (EC 1.1.1.153) |
|
|
|
STEAP1 PRSS24 STEAP |
|
Metalloreductase STEAP1 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 1) |
|
|
|
STEAP2 PCANAP1 STAMP1 UNQ6507/PRO23203 |
|
Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2) (SixTransMembrane protein of prostate 1) (Prostate cancer-associated protein 1) (Protein upregulated in metastatic prostate cancer) (PUMPCn) |
|
|
|
STEAP3 TSAP6 |
|
Metalloreductase STEAP3 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) (Dudulin-2) |
|
|
|
STEAP4 STAMP2 TNFAIP9 |
|
Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9) |
|
|
|
SUV39H1 KMT1A SUV39H |
|
Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.43) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) |
|
|
|
TDH |
|
Inactive L-threonine 3-dehydrogenase, mitochondrial |
|
|
|
TGDS |
|
dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46) |
|
|
|
TIPARP PARP7 |
|
TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP-ribose] polymerase 7) (PARP-7) |
|
|
|
TM7SF2 ANG1 |
|
Delta(14)-sterol reductase (Delta-14-SR) (EC 1.3.1.70) (C-14 sterol reductase) (Sterol C14-reductase) (Transmembrane 7 superfamily member 2) (Another new gene 1 protein) (Putative sterol reductase SR-1) |
|
|
|
TNKS PARP5A PARPL TIN1 TINF1 TNKS1 |
|
Tankyrase-1 (TANK1) (EC 2.4.2.30) (Tankyrase I) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Poly [ADP-ribose] polymerase 5A) |
|
|
|
TNKS2 PARP5B TANK2 TNKL |
|
Tankyrase-2 (TANK2) (EC 2.4.2.30) (Tankyrase II) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein) (Poly [ADP-ribose] polymerase 5B) |
|
|
|
TP53I3 PIG3 |
|
Quinone oxidoreductase PIG3 (EC 1.-.-.-) (Tumor protein p53-inducible protein 3) (p53-induced gene 3 protein) |
|
|
|
TRPM2 EREG1 KNP3 LTRPC2 TRPC7 |
|
Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Estrogen-responsive element-associated gene 1 protein) |
|
|
|
TRPT1 |
|
tRNA 2'-phosphotransferase 1 (EC 2.7.1.160) |
|
|
|
TSTA3 SDR4E1 |
|
GDP-L-fucose synthase (EC 1.1.1.271) (Protein FX) (Red cell NADP(H)-binding protein) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Short-chain dehydrogenase/reductase family 4E member 1) |
|
|
|
TXNDC2 SPTRX SPTRX1 |
|
Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) |
|
|
|
TXNRD1 GRIM12 KDRF |
|
Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Thioredoxin reductase TR1) (KM-102-derived reductase-like factor) (Gene associated with retinoic and interferon-induced mortality 12 protein) (Gene associated with retinoic and IFN-induced mortality 12 protein) (GRIM-12) |
|
|
|
TXNRD2 KIAA1652 TRXR2 |
|
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3) (TR-beta) (Selenoprotein Z) (SelZ) |
|
|
|
TXNRD3 TGR TRXR3 |
|
Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin reductase TR2) (Thioredoxin and glutathione reductase) (Fragment) |
|
|
|
UGDH |
|
UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) |
|
|
|
UROC1 |
|
Urocanate hydratase (Urocanase) (EC 4.2.1.49) (Imidazolonepropionate hydrolase) |
|
|
|
UXS1 UNQ2538/PRO6079 |
|
UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1) (UGD) |
|
|
|
XDH XDHA |
|
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase)] |
|
|
Riboflavin/Vitamin B2-dependent |
|
|||
|
|
ACAD10 |
|
Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) |
|
|
|
ACAD11 |
|
Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.99.-) |
|
|
|
ACAD8 ARC42 IBD |
|
Isobutyryl-CoA dehydrogenase, mitochondrial (EC 1.3.99.-) (Acyl-CoA dehydrogenase family member 8) (ACAD-8) (Activator-recruited cofactor 42 kDa component) (ARC42) |
|
|
|
ACAD9 |
|
Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9) (EC 1.3.99.-) |
|
|
|
ACADL |
|
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (LCAD) (EC 1.3.99.13) |
|
|
|
ACADM |
|
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.99.3) |
|
|
|
ACADS |
|
Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.99.2) (Butyryl-CoA dehydrogenase) |
|
|
|
ACADSB |
|
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.99.-) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase) |
|
|
|
ACADVL VLCAD |
|
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.99.-) |
|
|
|
ACOX1 ACOX |
|
Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX) |
|
|
|
ACOX2 |
|
Peroxisomal acyl-coenzyme A oxidase 2 (EC 1.17.99.3) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase) (Trihydroxycoprostanoyl-CoA oxidase) (THCA-CoA oxidase) (THCCox) |
|
|
|
ACOX3 BRCOX PRCOX |
|
Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Pristanoyl-CoA oxidase) (Branched-chain acyl-CoA oxidase) (BRCACox) |
|
|
|
ACOXL |
|
Acyl-coenzyme A oxidase-like protein (Acyl-CoA oxidase-like protein) (EC 1.3.3.-) |
|
|
|
AGPS AAG5 |
|
Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase) (Aging-associated gene 5 protein) |
|
|
|
AIFM1 AIF PDCD8 |
|
Apoptosis-inducing factor 1, mitochondrial (EC 1.-.-.-) (Programmed cell death protein 8) |
|
|
|
AIFM2 AMID PRG3 |
|
Apoptosis-inducing factor 2 (EC 1.-.-.-) (Apoptosis-inducing factor-like mitochondrion-associated inducer of death) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (p53-responsive gene 3 protein) |
|
|
|
AIFM3 AIFL |
|
Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein) |
|
|
|
AOX1 AO |
|
Aldehyde oxidase (EC 1.2.3.1) |
|
|
|
BLVRB FLR |
|
Flavin reductase (FR) (EC 1.5.1.30) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) |
|
|
|
CHDH |
|
Choline dehydrogenase, mitochondrial (CHD) (CDH) (EC 1.1.99.1) |
|
|
|
COQ6 CGI-10 |
|
Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-) |
|
|
|
CRY1 PHLL1 |
|
Cryptochrome-1 |
|
|
|
CRY2 KIAA0658 |
|
Cryptochrome-2 |
|
|
|
CYB5R1 NQO3A2 UNQ3049/PRO9865 |
|
NADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2) (Humb5R2) |
|
|
|
CYB5R2 |
|
NADH-cytochrome b5 reductase 2 (b5R.2) (EC 1.6.2.2) |
|
|
|
CYB5R3 DIA1 |
|
NADH-cytochrome b5 reductase 3 (Cytochrome b5 reductase) (B5R) (EC 1.6.2.2) (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form] |
|
|
|
CYB5R4 NCB5OR |
|
Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (cb5/cb5R) (N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein) |
|
|
|
CYB5RL |
|
NADH-cytochrome b5 reductase-like (EC 1.6.2.2) |
|
|
|
CYBB NOX2 |
|
Cytochrome b-245 heavy chain (EC 1.-.-.-) (p22 phagocyte B-cytochrome) (Neutrophil cytochrome b 91 kDa polypeptide) (Heme-binding membrane glycoprotein gp91phox) (CGD91-phox) (gp91-phox) (gp91-1) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Superoxide-generating NADPH oxidase heavy chain subunit) (NADPH oxidase 2) |
|
|
|
D2HGDH D2HGD |
|
D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-) |
|
|
|
DAK |
|
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.29) (Glycerone kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)] |
|
|
|
DAO DAMOX |
|
D-amino-acid oxidase (DAMOX) (DAAO) (DAO) (EC 1.4.3.3) |
|
|
|
DDO |
|
D-aspartate oxidase (DASOX) (EC 1.4.3.1) (DDO) |
|
|
|
DHCR24 KIAA0018 |
|
24-dehydrocholesterol reductase (EC 1.3.1.-) (3-beta-hydroxysterol delta-24-reductase) (Seladin-1) (Diminuto/dwarf1 homolog) |
|
|
|
DHODH |
|
Dihydroorotate dehydrogenase, mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) |
|
|
|
DLD GCSL LAD PHE3 |
|
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein) |
|
|
|
DMGDH |
|
Dimethylglycine dehydrogenase, mitochondrial (EC 1.5.99.2) (ME2GLYDH) |
|
|
|
DPYD |
|
Dihydropyrimidine dehydrogenase [NADP+] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase) |
|
|
|
DUOX1 DUOX LNOX1 THOX1 |
|
Dual oxidase 1 (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Large NOX 1) (Long NOX 1) (Thyroid oxidase 1) |
|
|
|
DUOX2 LNOX2 THOX2 |
|
Dual oxidase 2 (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Large NOX 2) (Long NOX 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) |
|
|
|
DUS1L |
|
tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-) |
|
|
|
DUS2L DUS2 |
|
tRNA-dihydrouridine synthase 2-like (hDUS2) (EC 1.-.-.-) (Up-regulated in lung cancer protein 8) (URLC8) |
|
|
|
DUS3L |
|
tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-) |
|
|
|
DUS4L |
|
tRNA-dihydrouridine synthase 4-like (EC 1.-.-.-) (pp35) |
|
|
|
ERO1L UNQ434/PRO865 |
|
ERO1-like protein alpha (ERO1-L-alpha) (ERO1-L) (EC 1.8.4.-) (Oxidoreductin-1-L-alpha) (Endoplasmic oxidoreductin-1-like protein) |
|
|
|
ERO1LB |
|
ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Oxidoreductin-1-L-beta) (Endoplasmic oxidoreductin-1-like protein B) |
|
|
|
ETFA |
|
Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) |
|
|
|
ETFB FP585 |
|
Electron transfer flavoprotein subunit beta (Beta-ETF) |
|
|
|
ETFDH |
|
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-ubiquinone oxidoreductase) (ETF-QO) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) |
|
|
|
FDXR ADXR |
|
NADPH:adrenodoxin oxidoreductase, mitochondrial (Adrenodoxin reductase) (AR) (EC 1.18.1.2) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase) |
|
|
|
FLAD1 PP591 |
|
FAD synthase (EC 2.7.7.2) (FMN adenylyltransferase) (FAD pyrophosphorylase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region] |
|
|
|
FMO1 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1) |
|
|
|
FMO2 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (FMO 1B1) (Dimethylaniline oxidase 2) |
|
|
|
FMO3 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (FMO form 2) (FMO II) (Dimethylaniline oxidase 3) |
|
|
|
FMO4 FMO2 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4) |
|
|
|
FMO5 |
|
Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5) |
|
|
|
FMO6P FMO6 |
|
Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6) |
|
|
|
FNBP4 FBP30 KIAA1014 |
|
Formin-binding protein 4 (Formin-binding protein 30) |
|
|
|
FOXRED1 FP634 |
|
FAD-dependent oxidoreductase domain-containing protein 1 |
|
|
|
FOXRED2 ERFAD |
|
FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation) |
|
|
|
GCDH |
|
Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.99.7) |
|
|
|
GFER ALR HERV1 HPO |
|
FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin) |
|
|
|
GPD2 |
|
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPDH-M) (GPD-M) (EC 1.1.5.3) (mtGPD) |
|
|
|
GSR GLUR GRD1 |
|
Glutathione reductase, mitochondrial (GRase) (GR) (EC 1.8.1.7) |
|
|
|
HAO1 GOX1 HAOX1 |
|
Hydroxyacid oxidase 1 (HAOX1) (EC 1.1.3.15) (Glycolate oxidase) (GOX) |
|
|
|
HAO2 HAOX2 GIG16 |
|
Hydroxyacid oxidase 2 (HAOX2) (EC 1.1.3.15) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) (Cell growth-inhibiting gene 16 protein) |
|
|
|
IL4I1 FIG1 UNQ636/PRO1265 |
|
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Interleukin-4-induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1) |
|
|
|
IVD |
|
Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.99.10) |
|
|
|
IYD C6orf71 DEHAL1 |
|
Iodotyrosine dehalogenase 1 (IYD-1) (EC 1.-.-.-) |
|
|
|
KDM1A AOF2 KDM1 KIAA0601 LSD1 |
|
Lysine-specific histone demethylase 1A (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110) |
|
|
|
KDM1B AOF1 C6orf193 LSD2 |
|
Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Lysine-specific histone demethylase 2) (Flavin-containing amine oxidase domain-containing protein 1) |
|
|
|
KMO |
|
Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase) |
|
|
|
L2HGDH C14orf160 |
|
L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin) |
|
|
|
LDHD |
|
Probable D-lactate dehydrogenase, mitochondrial (Lactate dehydrogenase D) (DLD) (EC 1.1.2.4) |
|
|
|
MAOA |
|
Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A) |
|
|
|
MAOB |
|
Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) |
|
|
|
MICAL1 MICAL NICAL |
|
NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1) |
|
|
|
MICAL2 KIAA0750 |
|
Protein MICAL-2 |
|
|
|
MICAL3 KIAA0819 KIAA1364 |
|
Protein MICAL-3 |
|
|
|
MTHFR |
|
Methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
|
|
MTO1 CGI-02 |
|
Protein MTO1 homolog, mitochondrial |
|
|
|
MTRR |
|
Methionine synthase reductase (MSR) (EC 1.16.1.8) |
|
|
|
NDOR1 NR1 |
|
NADPH-dependent diflavin oxidoreductase 1 (EC 1.6.-.-) (Novel reductase 1) (NADPH-dependent FMN and FAD-containing oxidoreductase) |
|
|
|
NDUFA10 |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (NADH-ubiquinone oxidoreductase 42 kDa subunit) (Complex I-42kD) (CI-42kD) |
|
|
|
NDUFA9 NDUFS2L |
|
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (NADH-ubiquinone oxidoreductase 39 kDa subunit) (Complex I-39kD) (CI-39kD) |
|
|
|
NDUFV1 UQOR1 |
|
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase 51 kDa subunit) (Complex I-51kD) (CI-51kD) (NADH dehydrogenase flavoprotein 1) |
|
|
|
NOS1 |
|
Nitric oxide synthase, brain (EC 1.14.13.39) (bNOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) |
|
|
|
NOS2 NOS2A |
|
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Hepatocyte NOS) (HEP-NOS) |
|
|
|
NOS3 |
|
Nitric oxide synthase, endothelial (EC 1.14.13.39) (Endothelial NOS) (eNOS) (EC-NOS) (NOS type III) (NOSIII) (Constitutive NOS) (cNOS) |
|
|
|
NOX1 MOX1 NOH1 |
|
NADPH oxidase 1 (NOX-1) (EC 1.-.-.-) (NOH-1) (NADH/NADPH mitogenic oxidase subunit P65-MOX) (Mitogenic oxidase 1) (MOX-1) |
|
|
|
NOX3 MOX2 |
|
NADPH oxidase 3 (EC 1.6.3.-) (gp91phox homolog 3) (GP91-3) (Mitogenic oxidase 2) (MOX-2) |
|
|
|
NOX4 RENOX |
|
NADPH oxidase 4 (EC 1.6.3.-) (Kidney superoxide-producing NADPH oxidase) (Kidney oxidase-1) (KOX-1) (Renal NAD(P)H-oxidase) |
|
|
|
NOX5 |
|
NADPH oxidase 5 (EC 1.6.3.-) |
|
|
|
NQO1 DIA4 NMOR1 |
|
NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (QR1) (NAD(P)H:quinone oxidoreductase 1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase) |
|
|
|
NQO2 NMOR2 |
|
Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.99.2) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2) |
|
|
|
OXNAD1 |
|
Oxidoreductase NAD-binding domain-containing protein 1 (EC 1.-.-.-) |
|
|
|
PAOX PAO UNQ1923/PRO4398 |
|
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase) |
|
|
|
PCYOX1 KIAA0908 PCL1 UNQ597/PRO1183 |
|
Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase) |
|
|
|
PCYOX1L PSEC0105 |
|
Prenylcysteine oxidase-like (EC 1.8.3.-) |
|
|
|
PDP2 KIAA1348 |
|
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (PDP 2) (EC 3.1.3.43) (Pyruvate dehydrogenase phosphatase catalytic subunit 2) (PDPC 2) |
|
|
|
PIPOX LPIPOX PSO |
|
Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) |
|
|
|
PNPO |
|
Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase) |
|
|
|
POR CYPOR |
|
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) |
|
|
|
PPCDC COAC MDS018 UNQ9365/PRO34154 |
|
Phosphopantothenoylcysteine decarboxylase (PPC-DC) (EC 4.1.1.36) (CoaC) |
|
|
|
PPOX |
|
Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) |
|
|
|
PRODH PIG6 POX2 |
|
Proline dehydrogenase, mitochondrial (EC 1.5.99.8) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein) |
|
|
|
PRODH2 |
|
Probable proline dehydrogenase 2 (EC 1.5.99.8) (Probable proline oxidase 2) (Kidney and liver proline oxidase 1) (HsPOX1) |
|
|
|
PYROXD1 |
|
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) |
|
|
|
QSOX1 QSCN6 UNQ2520/PRO6013 |
|
Sulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6) |
|
|
|
QSOX2 QSCN6L1 SOXN |
|
Sulfhydryl oxidase 2 (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase) |
|
|
|
RETSAT UNQ439/PRO872 |
|
All-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat) |
|
|
|
RFK |
|
Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) |
|
|
|
RNLS C10orf59 |
|
Renalase (EC 1.4.-.-) (Monoamine oxidase-C) (MAO-C) |
|
|
|
SARDH DMGDHL1 |
|
Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.99.1) (BPR-2) |
|
|
|
SDHA SDH2 SDHF |
|
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp) |
|
|
|
SDHAF2 C11orf79 PGL2 SDH5 |
|
Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (Succinate dehydrogenase subunit 5, mitochondrial) (hSDH5) |
|
|
|
SMOX C20orf16 SMO UNQ3039/PRO9854 |
|
Spermine oxidase (EC 1.5.3.16) (Polyamine oxidase 1) (PAO-1) (PAOh1) |
|
|
|
SQLE ERG1 |
|
Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE) |
|
|
|
SQRDL CGI-44 |
|
Sulfide:quinone oxidoreductase, mitochondrial (EC 1.-.-.-) |
|
|
|
STEAP1 PRSS24 STEAP |
|
Metalloreductase STEAP1 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 1) |
|
|
|
STEAP2 PCANAP1 STAMP1 UNQ6507/PRO23203 |
|
Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2) (SixTransMembrane protein of prostate 1) (Prostate cancer-associated protein 1) (Protein upregulated in metastatic prostate cancer) (PUMPCn) |
|
|
|
STEAP3 TSAP6 |
|
Metalloreductase STEAP3 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) (Dudulin-2) |
|
|
|
STEAP4 STAMP2 TNFAIP9 |
|
Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9) |
|
|
|
TXNRD1 GRIM12 KDRF |
|
Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Thioredoxin reductase TR1) (KM-102-derived reductase-like factor) (Gene associated with retinoic and interferon-induced mortality 12 protein) (Gene associated with retinoic and IFN-induced mortality 12 protein) (GRIM-12) |
|
|
|
TXNRD2 KIAA1652 TRXR2 |
|
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3) (TR-beta) (Selenoprotein Z) (SelZ) |
|
|
|
TXNRD3 TGR TRXR3 |
|
Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin reductase TR2) (Thioredoxin and glutathione reductase) (Fragment) |
|
|
|
XDH XDHA |
|
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase)] |
|
|
Thiamine/Vitamin B1 dependent |
||||
|
|
DHTKD1 KIAA1630 |
|
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (EC 1.2.4.2) (Dehydrogenase E1 and transketolase domain-containing protein 1) |
|
|
|
ENTPD5 CD39L4 PCPH |
|
Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (EC 3.6.1.6) (Nucleoside diphosphatase) (CD39 antigen-like 4) (ER-UDPase) |
|
|
|
HACL1 HPCL HPCL2 PHYH2 HSPC279 |
|
2-hydroxyacyl-CoA lyase 1 (EC 4.1.-.-) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2) |
|
|
|
ILVBL AHAS |
|
Acetolactate synthase-like protein (EC 2.2.1.-) (IlvB-like protein) |
|
|
|
BCKDHA |
|
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A) |
|
|
|
OGDH |
|
2-oxoglutarate dehydrogenase, mitochondrial (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) |
|
|
|
PDHA2 PDHAL |
|
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (EC 1.2.4.1) (PDHE1-A type II) |
|
|
|
PDHA1 PHE1A |
|
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I) |
|
|
|
PDHB PHE1B |
|
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1) |
|
|
|
OGDHL KIAA1290 |
|
2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.-) (Alpha-ketoglutarate dehydrogenase-like) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) |
|
|
|
SLC19A2 THT1 TRMA |
|
Thiamine transporter 1 (ThTr-1) (ThTr1) (Thiamine carrier 1) (TC1) (Solute carrier family 19 member 2) |
|
|
|
SLC19A3 |
|
Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3) |
|
|
|
THTPA |
|
Thiamine-triphosphatase (ThTPase) (EC 3.6.1.28) |
|
|
|
TKTL1 TKR TKT2 |
|
Transketolase-like protein 1 (EC 2.2.1.1) (Transketolase 2) (TK 2) (Transketolase-related protein) |
|
|
|
TKTL2 |
|
Transketolase-like protein 2 (EC 2.2.1.1) |
|
|
|
TKT |
|
Transketolase (TK) (EC 2.2.1.1) |
|
|
|
SLC25A19 DNC MUP1 |
|
Mitochondrial thiamine pyrophosphate carrier (Solute carrier family 25 member 19) (Mitochondrial uncoupling protein 1) |
|
|
|
TPK1 |
|
Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Thiamine pyrophosphokinase 1) (Placental protein 20) (PP20) |
|
|
|
accession BAG60459 |
|
unnamed hypothetical protein based on cDNA clone |
|
|
|
accession BAC87051 |
|
unnamed hypothetical protein based on cDNA clone |
|
|
|
accession CAH56215 |
|
unnamed hypothetical protein based on cDNA clone |
|
